ea0016s20.6 | Translational highlights | ECE2008
Kevenaar Marlies E
, Laven Joop SE
, Fong Sharon Lie
, Uitterlinden Andre G
, de Jong Frank H
, Themmen Axel PN
, Visser Jenny A
Polycystic ovary syndrome (PCOS) is characterized by anovulation, elevated levels of circulating androgens and polycystic ovaries. Although the etiology of PCOS is poorly understood, the common denominator is a disturbance in the selection of the dominant follicle. In PCOS women serum Anti-Müllerian Hormone (AMH) levels are elevated. Since AMH reduces FSH sensitivity of growing follicles, the elevated AMH levels in PCOS patients may contribute to the disturbed follicle se...